ايمان عبد الحفيظ محمود ابو زيد الجحدلي


علوم المختبرات والتقنية الإكلينيكية
Eman.a@tu.edu.sa
Certificate Name Certificate University Certificate Date
الدكتوراه في Cancer biology State University of New York at Buffalo 04/08/2022
Research Name Research Date Submitted Research Link
Mutant Kras as a Biomarker Plays a Favorable Role in FL118-Induced Apoptosis, Reactive Oxygen Species (ROS) Production and Modulation of Survivin, Mcl-1 and XIAP in Human Bladder Cancer 2022-11-01 12:00:00 AM Mutant Kras as a Biomarker Plays a Favorable Role in FL118-Induced Apoptosis, Reactive Oxygen Species (ROS) Production and Modulation of Survivin, Mcl-1 and XIAP in Human Bladder Cancer
Molecular Glues: Capable Protein-Binding Small Molecules That Can Change Protein-Protein Interactions and Interactomes for the Potential Treatment of Human Cancer and Neurodegenerative Diseases 2022-06-01 12:00:00 AM Molecular Glues: Capable Protein-Binding Small Molecules That Can Change Protein-Protein Interactions and Interactomes for the Potential Treatment of Human Cancer and Neurodegenerative Diseases
FL118, acting as a 'molecular glue degrader', binds to dephosphorylates and degrades the oncoprotein DDX5 (p68) to control c-Myc, survivin and mutant Kras against colorectal and pancreatic cancer with 2022-05-01 12:00:00 AM FL118, acting as a 'molecular glue degrader', binds to dephosphorylates and degrades the oncoprotein DDX5 (p68) to control c-Myc, survivin and mutant Kras against colorectal and pancreatic cancer with
Kidney cancer biomarkers and targets for therapeutics: survivin (BIRC5), XIAP, MCL-1, HIF1?, HIF2?, NRF2, MDM2, MDM4, p53, KRAS and AKT in renal cell carcinoma 2021-08-01 12:00:00 AM Kidney cancer biomarkers and targets for therapeutics: survivin (BIRC5), XIAP, MCL-1, HIF1?, HIF2?, NRF2, MDM2, MDM4, p53, KRAS and AKT in renal cell carcinoma
Kras mutation subtypes distinctly affect colorectal cancer cell sensitivity to FL118, a novel inhibitor of survivin, Mcl-1, XIAP, cIAP2 and MdmX 2021-07-01 12:00:00 AM Kras mutation subtypes distinctly affect colorectal cancer cell sensitivity to FL118, a novel inhibitor of survivin, Mcl-1, XIAP, cIAP2 and MdmX
Cancer therapeutics using survivin BIRC5 as a target: what can we do after over two decades of study? 2019-08-01 12:00:00 AM Cancer therapeutics using survivin BIRC5 as a target: what can we do after over two decades of study?
Role of Chromatin Damage and Chromatin Trapping of FACT in Mediating the Anticancer Cytotoxicity of DNA-Binding Small-Molecule Drugs 2018-03-01 12:00:00 AM Role of Chromatin Damage and Chromatin Trapping of FACT in Mediating the Anticancer Cytotoxicity of DNA-Binding Small-Molecule Drugs
Tumor p38MAPK signaling enhances breast carcinoma vascularization and growth by promoting expression and deposition of pro-tumorigenic factors 2017-06-01 12:00:00 AM Tumor p38MAPK signaling enhances breast carcinoma vascularization and growth by promoting expression and deposition of pro-tumorigenic factors
Place Name Experince From To
Cource Name place Cource Date
O EFFECTIVE TEACHING WORKSHOP SERIES, CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE (CTSA), UNIVERSITY AT BUFFALO. 03/09/2020
O ACADEMIC LEADERSHIP DEVELOPMENT WORKSHOP, ACADEMIC LEADERSHIP CENTER, MINISTRY OF EDUCATION AT KINGDOM OF SAUDI ARABIA, WASHINGTON D.C. Ministry of Education 16/05/2019
O STATISTICAL WORKSHOP SERIES, CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE (CTSA), UNIVERSITY AT BUFFALO. 09/08/2018
Award/invention Doner Place Date
Committee Name Committee Type Join Date
لجنة الأنشطة الطلابية داخل الجامعة 04/09/2022
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